EVALUATION OF MOLLUSCICIDAL ACTIVITIES OF CRUDE AND ALKALOIDAL FRACTION OF ANOGEISSUS LEIOCARPUS (AFRICAN BITCH) AND PSEUDOCEDRELA KOTSCHYI (DRY ZONE CEDAR) ON VECTOR OF SCHISTOSOMIASIS
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 5000
ABSTRACT
Over the years, the use of plant-based molluscicides has received substantial consideration in the satisfaction for cost-effective alternatives to chemotherapy and synthetic molluscicides in schistosomiasis control. This study was aimed at evaluating the molluscicidal potentials of crude and Alkaloidal fractions of Anogeissus leiocarpus and Pseudocedrela kostchyi against vector of schistosomiasis. Both aqueous and methanol crude extracts of the plants were tested for the presence of bioactive metabolites. Ten snails each was exposed to different concentrations (10 mg/L, 20 mg/L, 40 mg/L, 80 mg/L, 160 mg/L, 200 mg/L and 300 mg/L) of aqueous, methanol and alkaloid extracts of Anogeissus leiocarpus and Pseudocedrela kostchyi for the interval of 40 minutes, 24 hours and 72 hours respectively. Fifty other snails were also exposed to 200 mL of distilled water for 24 hours as control. The results indicated the presence of phytochemicals such as flavonoid, Tannis, Saponins, Alkaloids and terpenoids in both aqueous and methanol extract of both plants. Steroid was only present in methanol extract. Cardia glycoside was absent in aqueous extract of the extracts. The results showed dose dependent activities with highest dose having a significant (P<0.05) highest snail mortality. The two plants extracts showed appreciable molluscicidal efficacies against the two exposed snail species with LC50 of 157.29, 88.56, and 240.03mg/L for aqueous, methanol and Alkaloidal fraction of A. leiocarpus against B. pfeifferi and LC50 of 128.73, 78.07 and 344.02mg/L for P. koschyi respectively. There was a significant decrease in the level of Alamine transaminase (ALT) and Aspartate triaminase (AST) in the tissue of the exposed snail compared to the control. Based on the findings of this study, there is need to examine the Histoachitecture of the exposed snail in other to ascertain the observed mechanism of action found in the alteration of the tissue enzymes
Related Project Materials
An Evaluation of Pricing Discrimination Practices Among Nigerian Service Providers
Background of the Study
Pricing discrimination refers to the practice of charging different prices to different consumers for the same pr...
The effect of technological advancements on investment banking processes: a case study of Union Bank Nigeria
Background of the Study
Technological advancements have become a critical catalyst for change in the financial services se...
The impact of teacher training programs on online education delivery in secondary schools in Gusau Central LGA, Zamfara State
Background of the Study:
Teacher training programs are critical in ensuring effective online education delivery, especially...
An investigation into the role of science competitions in improving STEM education in Mobbar LGA, Borno State
Background of the Study
Science competitions have emerged as dynamic platforms for fostering innovation, critical thinking...
Enhancing IoT-Based Smart Automatic Water Dispensing in Secondary Schools in Sokoto South LGA, Sokoto State
Background of the study:
Water is an essential resource in every educational institution, and ensuring its efficient and hy...
The effect of digital innovation on operational efficiency in Islamic banking
Background of the Study
Digital innovation has become a transformative force in the banking industry, and...
AN INVESTIGATION OF CHARACTERIZATION AND ISOLATION OF FUNGI ASSOCIATED WITH “SPOILED” TOMATOES IN GWAGWALADA
INTRODUCTION
Vegetables are an essential food product that are both economically important and nutritionally significant...
BANK INSPECTION AND ENFORCMENT OF BANKING REGULATION IN NIGERIAN BANKS
ABSTRACT
Just as every sector of the economy is eager to improve her condition through various research work, it is...
Analysis of Genetic Variations in Malaria Resistance Using Computational Biology: A Case Study of Ahmadu Bello University, Zaria, Kaduna State
Background of the Study
Malaria remains a leading cause of morbidity and mortality in Nigeria, and understanding the genet...
Design and Implementation of an IoT-Based Smart Poultry Monitoring System in Gusau LGA, Zamfara State
Background of the Study :
Poultry farming is a vital component of agriculture in many regions, including Gusau LGA, Zamfara...
