EVALUATION OF MOLLUSCICIDAL ACTIVITIES OF CRUDE AND ALKALOIDAL FRACTION OF ANOGEISSUS LEIOCARPUS (AFRICAN BITCH) AND PSEUDOCEDRELA KOTSCHYI (DRY ZONE CEDAR) ON VECTOR OF SCHISTOSOMIASIS
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 5000
ABSTRACT
Over the years, the use of plant-based molluscicides has received substantial consideration in the satisfaction for cost-effective alternatives to chemotherapy and synthetic molluscicides in schistosomiasis control. This study was aimed at evaluating the molluscicidal potentials of crude and Alkaloidal fractions of Anogeissus leiocarpus and Pseudocedrela kostchyi against vector of schistosomiasis. Both aqueous and methanol crude extracts of the plants were tested for the presence of bioactive metabolites. Ten snails each was exposed to different concentrations (10 mg/L, 20 mg/L, 40 mg/L, 80 mg/L, 160 mg/L, 200 mg/L and 300 mg/L) of aqueous, methanol and alkaloid extracts of Anogeissus leiocarpus and Pseudocedrela kostchyi for the interval of 40 minutes, 24 hours and 72 hours respectively. Fifty other snails were also exposed to 200 mL of distilled water for 24 hours as control. The results indicated the presence of phytochemicals such as flavonoid, Tannis, Saponins, Alkaloids and terpenoids in both aqueous and methanol extract of both plants. Steroid was only present in methanol extract. Cardia glycoside was absent in aqueous extract of the extracts. The results showed dose dependent activities with highest dose having a significant (P<0.05) highest snail mortality. The two plants extracts showed appreciable molluscicidal efficacies against the two exposed snail species with LC50 of 157.29, 88.56, and 240.03mg/L for aqueous, methanol and Alkaloidal fraction of A. leiocarpus against B. pfeifferi and LC50 of 128.73, 78.07 and 344.02mg/L for P. koschyi respectively. There was a significant decrease in the level of Alamine transaminase (ALT) and Aspartate triaminase (AST) in the tissue of the exposed snail compared to the control. Based on the findings of this study, there is need to examine the Histoachitecture of the exposed snail in other to ascertain the observed mechanism of action found in the alteration of the tissue enzymes
Related Project Materials
THE EFFECT OF TAXATION ON MANUFACTURING FIRMS
ABSTRACT
This research work was carried out to examine the effect of taxation on manufacturing firms. T...
DESIGN AND CONSTRUCTION OF GRAIN GRINDING MACHINE
Background of the Study
The grinding of grain occurs by the application of mechanical forces that alter the structure of...
THE IMPACT OF INTEREST RATE ON HOUSING FINANCE IN NIGERIA
ABSTRACT
Housing remains to be a critical and essential sector for nearly all economie...
EFFECT OF PARTNERSHIP AND JOINT VENTURE BUSINESS IN SMALL SCALE BUSINESS IN NIGERIA, PROBLEM AND PROSPECT
ABSTRACT
Formation of joint ventures between SMEs is one of the recent efforts in improving SME growth in Nigeria and ad...
ASSESSING THE IMPACT OF EARLY CHILDHOOD EDUCATION ON PARENTAL INVOLVEMENT IN SCHOOL GOVERNANCE
ABSTRACT: Assessing the impact of early childhood education on paren...
THE PROBLEMS AND PROSPECTS OF SOCIAL MARKETING IN NIGERIA MANUFACTURING ORGANISATION
ABSTRACT
The aim of this research work is to appraise “problems and prospects of social mar...
CORPORATE SOCIAL RESPONSIBILITY REPORTING AND EXECUTIVE COMPENSATION IN NIGERIA
Background to the study
The increased interest in the role of business in society today has been promp...
THE ROLE OF POLITICAL PARTIES IN DEMOCRATIC GOVERNANCE IN NIGERIA: A CASE STUDY OF PDP: 1999-2007
ABSTRACT
There is a profound paradox about the Peoples Democratic Party (PDP) in Nigeria. The party, which earned the re...
A SURVEY OF CAREER CHOICE DETERMINANTS AMONG SECONDARY SCHOOLS STUDENTS
ABSTRACT
Career selection is one of many important choices students will make in determining future plans; this decision...
SECURITY CHALLENGES AND ECONOMY OF THE NIGERIAN STATE
Abstract
This study examines security challenges and economy of the Nigerian state . Th...
